Abstract: In the construction of underground shield tunnels, a large amount of slurry with high water content is produced. Due to the high moisture content of the slurry and the additives such as bentonite and foaming agent, the slurry is characterized by high water content, low permeability and strong plastic flow. It is prone to environmental pollution problems such as throwing and dripping during transportation, and it occupies a lot of land resources when the slurry is piled up. Sometimes improper stacking also pollutes the environment and even forms geological disasters. In this work, the experimental research on the mud-water dehydration technology of the tunnel shield slurry is carried out, and an electro-osmosis combined with vacuum negative pressure drainage test device is developed, in which vacuum negative pressure, electro-osmosis and vacuum negative pressure incorporated with electro-osmosis technology are used for the slurry that is initially treated by sedimentation to conduct mud-water dehydration test. The test results show that the drainage effect of the combined method is better than that of the single method alone. The combined method not only discharges seepage bound water in the slurry but also discharges free water. The moisture content of the treated slurry is greatly reduced (close to the plastic limit), and the slurry is effectively hardened. The order of the mud-water dehydration method is first to perform the electro-osmotic method and then to perform the drainage method. This research effectively solves the problem of the mud-water dehydration, and is conducive to green and safe transportation and effectively reduce transportation costs. More importantly, the treated slurry can be directly utilized.