Abstract: The dynamic response of an anti-dip layered rock slope is examined by using shake table model tests. By inputting sine waves of different frequencies, excitation intensity and holding time, the acceleration of response of the model slope is monitored, and the influence of frequency on the dynamic response characteristics of acceleration of the model slope is analyzed emphatically. The results show that ① there are two different forms of the influence of frequency of seismic wave on dynamic response of the model slope. When frequency of the input wave is less than or equal to the natural frequency of the model slope, with the increasing frequency, the elevation amplification effect of the model slope is enhanced. ② When frequency of the input wave is greater than the natural frequency of the model slope, with the increasing frequency, the elevation amplification effect of the model slope is weakened or even disappears. The dynamic response of the model slope decreases first and then increases with the increasing the elevation. The acceleration response at the bottom of the model slope is relatively stronger, even greater than the response intensity of the upper and middle parts. The acceleration magnification factor at each point of the model slope is almost all less than 1.0. ③ The wave whose frequency is less than or equal to the natural frequency often causes deformation and failure of the top and superficial parts of the model slope and the wave whose frequency is greater than the natural frequency causes the deformation of the bottom of the model slope. ④ Frequency, excitation intensity and holding time have an influence on the dynamic response of the model slope, but the frequency has the most significant impact, followed by the intensity of vibration, and the impact of holding time is the weakest.